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Updated: May 29, 2026 at 3:36 PM

Amboss | One-Minute Telegram️

A biweekly newsletter that presents the newest medical research condensed into just one minute of reading... A journal club for busy doctors, with the latest research distilled down to just one minute of reading. For contact: 👉 @Amboss_Team

@amboss_medical_news is a growing community focused on minute and presents and related topics

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Amboss | One-Minute Telegram️

Mar 20, 2026, 04:14 AM

[poll]

Amboss | One-Minute Telegram️

Mar 20, 2026, 04:14 AM

A 23-year-old man presents to his primary care physician with 2 weeks of headache, palpitations, and excessive sweating. He has no past medical history and his family history is significant for clear cell renal cell carcinoma in his father as well as retinal hemangioblastomas in his older sister. On presentation his temperature is 99°F (37.2°C), blood pressure is 181/124 mmHg, pulse is 105/min, and respirations are 18/min. After administration of appropriate medications, he is taken emergently for surgical removal of a mass that was detected by abdominal computed tomography scan. A mutation on which of the following chromosomes would most likely be seen in this patient?

Amboss | One-Minute Telegram️

Mar 20, 2026, 04:14 AM

[poll]

Amboss | One-Minute Telegram️

Mar 20, 2026, 04:14 AM

Great news for your morning mug! A massive 43-year study suggests your daily caffeine fix is doing more than just waking you up—it's actually shielding your brain from long-term decline. So, go ahead and grab that refill guilt-free. Turns out, your coffee habit is basically a genius-level brain hack. ☕️

👇 Check it out:
https://www.sciencedaily.com/releases/2026/03/260318033138.htm

Amboss | One-Minute Telegram️

Mar 20, 2026, 04:14 AM

[poll]

Amboss | One-Minute Telegram️

Mar 20, 2026, 04:14 AM

We finally know how that Alzheimer’s drug pulls its weight. Instead of just cleaning up big brain plaques, it targets the tiny, toxic protein seeds before they cause real chaos. Think of it as a bouncer stopping trouble at the door rather than cleaning up after the riot. Pretty clever, right? 🧠✨

👇 Check it out:
https://www.sciencedaily.com/releases/2026/03/260317064457.htm

Amboss | One-Minute Telegram️

Mar 20, 2026, 04:14 AM

A 17-year-old woman presents to the emergency department with dysuria. She denies any hematuria or dyspareunia. Her last menstrual period was 3 weeks ago, and she denies any recent sexual activity. Her temperature is 99.7°F (37.6°F), blood pressure is 127/67 mmHg, pulse is 90/min, and respirations are 17/min. An unusual odor is detected on inspection of the vagina and some gray discharge is noted. Speculum exam reveals a normal cervix and a bimanual exam is unremarkable for adnexal masses or tenderness. What is the next best step in management?

Amboss | One-Minute Telegram️

Mar 20, 2026, 04:14 AM

A 55-year-old man presents to the emergency department with shortness of breath and fatigue. His symptoms began insidiously and progressively worsened over the course of a month. He becomes short of breath when climbing the stairs or performing low-intensity exercises. He also needs to rest on multiple pillows in order to comfortably sleep. A few weeks ago he developed fever, malaise, and chest pain. Medical history is significant for hypertension, hypercholesterolemia, type II diabetes, and bariatric surgery performed 10 years ago. He is taking lisinopril, atorvastatin, and metformin. He drinks alcohol occasionally and does not smoke. He tried cocaine 3 days ago for the first time and has not used the illicit drug since. Physical exam is significant for bibasilar crackles, an S3 heart sound, and a laterally displaced cardiac apex. He has normal muscle tone throughout, 2+ reflexes, and an intact sensory exam. Which of the following is most likely the cause of this patient's symptoms

Amboss | One-Minute Telegram️

Mar 20, 2026, 04:14 AM

[poll]

Amboss | One-Minute Telegram️

Mar 20, 2026, 04:14 AM

A 19-year-old man with a history of generalized tonic-clonic seizures comes to the physician for a routine health maintenance examination. He is a known user of intravenous cocaine. His vital signs are within normal limits. Physical examination shows multiple hyperpigmented lines along the forearms. Oral examination shows marked overgrowth of friable, ulcerated gingival mucosa. Which of the following is the most likely cause of this patient's oral examination findings?

Amboss | One-Minute Telegram️

Mar 19, 2026, 12:29 PM

Forget the doom-scrolling; scientists found that just 24 minutes of specially composed music can significantly tank your anxiety levels. It’s basically a prescription-strength playlist for your brain. So, if life feels overwhelming, just pop on some headphones and let the frequencies do the heavy lifting. Who knew peace had a runtime? 🎵✨

👇 Check it out:
https://www.sciencedaily.com/releases/2026/03/260315225133.htm

Amboss | One-Minute Telegram️

Mar 19, 2026, 12:29 PM

[poll]

Amboss | One-Minute Telegram️

Mar 19, 2026, 12:29 PM

Parents are leaning hard on melatonin to win the bedtime battle, but doctors are officially sounding the alarm. Between inconsistent dosages in those tasty gummies and a total lack of long-term safety data, it might be time to ditch the sleepy candy and stick to a boring book. 🌙💤

👇 Check it out:
https://www.sciencedaily.com/releases/2026/03/260315004407.htm

Amboss | One-Minute Telegram️

Mar 19, 2026, 12:29 PM

A 17-year-old previously healthy, athletic male suddenly falls unconscious while playing soccer. His athletic trainer comes to his aid and notes that he is pulseless. He begins performing CPR on the patient until the ambulance arrives but the teenager is pronounced dead when the paramedics arrived. Upon investigation of his primary care physician's office notes, it was found that the child had a recognized murmur that was ruled to be "benign." Which of the following conditions would have increased the intensity of the murmur?

Amboss | One-Minute Telegram️

Mar 19, 2026, 12:29 PM

[poll]

Amboss | One-Minute Telegram️

Mar 18, 2026, 03:07 AM

[poll]

Amboss | One-Minute Telegram️

Mar 18, 2026, 03:07 AM

A 5-year-old boy presents to the emergency department with a sore throat and trouble breathing. His mother states that his symptoms started last night and have rapidly been worsening. The patient is typically healthy, has received all his childhood immunizations, and currently takes a daily multivitamin. His temperature is 103°F (39.4°C), blood pressure is 100/64 mmHg, pulse is 155/min, respirations are 29/min, and oxygen saturation is 95% on room air. Physical exam is notable for an ill-appearing child who is drooling and is leaning forward to breathe. He does not answer questions and appears very uncomfortable. He will not comply with physical exam to open his mouth for inspection of the oropharynx. Which of the following is the most likely infectious etiology of this patient's symptoms?

Amboss | One-Minute Telegram️

Mar 18, 2026, 03:07 AM

[poll]

Amboss | One-Minute Telegram️

Mar 18, 2026, 03:07 AM

A 48-year-old woman comes to the physician for the evaluation of 24-hour blood pressure monitoring results. Over the last 3 months, she has had intermittent nausea, decreased appetite, and increasing weakness and fatigue during the day. She has been treated twice for kidney stones within the past year. Her current medications include lisinopril, amlodipine, and furosemide. She is 178 cm (5 ft 10 in) tall and weighs 97 kg (214 lb); BMI is 31 kg/m2. Her blood pressure is 152/98 mm Hg. Physical examination shows no abnormalities. Serum studies show:
Na+ 141 mEq/L
Cl− 101 mEq/L
K+ 4.5 mEq/L
HCO3− 24 mEq/L
Calcium 12.9 mg/dL
Creatinine 1.0 mg/dL
Twenty-four-hour blood pressure monitoring indicates elevated nocturnal blood pressure. Further evaluation is most likely to show which of the following findings?"

Amboss | One-Minute Telegram️

Mar 18, 2026, 03:07 AM

[poll]

Amboss | One-Minute Telegram️

Mar 18, 2026, 03:07 AM

A 58-year-old woman comes to the physician for evaluation of worsening fatigue for 1 week. She also has a 1-year history of hand pain and stiffness. Four months ago, she started a new medication for these symptoms. Medications used prior to that included ibuprofen, prednisone, and hydroxychloroquine. Examination shows a subcutaneous nodule on her left elbow and old joint destruction with Boutonniere deformity. Her hemoglobin concentration is 10.1 g/dL, leukocyte count is 3400/mm3, and platelet count is 101,000/mm3. Methylmalonic acid levels are normal. Which of the following could have prevented this patient's laboratory abnormalities?

Amboss | One-Minute Telegram️

Mar 17, 2026, 01:00 PM

A 25-year-old woman is brought to a psychiatrist’s office by her husband who states that he is worried about her recent behavior, as it has become more violent. The patient’s husband states that his family drove across the country to visit them and that his wife ‘threatened his parents with a knife’ at dinner last night. Police had to be called to calm her down. He states that she has been acting ‘really crazy’ for the last 9 months, and the initial behavior that caused him alarm was her admission that his deceased sister was talking to her through a decorative piece of ceramic art in the living room. Initially, he thought she was joking, but soon realized her complaints of ‘hearing ghosts’ talking to her throughout the house were persisting and ‘getting worse’. There was also a 4-week period where she experienced insomnia and an unintentional weight loss of 12 pounds. She seemed sad throughout these episodes, and, according to her husband, was complaining of feeling ‘worthless’. Her general hygiene has also suffered from her recent lack of motivation and she insists that the ‘ghosts’ are asking her to kill as many people as she can so they won’t be alone in the house. Her husband is extremely concerned that she may harm herself or someone else. He states that she currently does not take any medications or illicit drugs as far as he knows. She does not smoke or drink alcohol. The patient herself does not make eye contact or want to speak to the psychiatrist, allowing her husband to speak on her behalf. Which of the following is the most likely diagnosis in this patient?

Amboss | One-Minute Telegram️

Mar 17, 2026, 01:00 PM

A 23-year-old male presents with complaints of polydipsia and frequent, large-volume urination. Laboratory testing does not demonstrate any evidence of diabetes; however, a reduced urine osmolality of 120 mOsm/L is measured. Which of the following findings on a desmopressin test would be most consistent with a diagnosis of central diabetes insipidus?

Amboss | One-Minute Telegram️

Mar 17, 2026, 01:00 PM

[poll]

Amboss | One-Minute Telegram️

Mar 17, 2026, 01:00 PM

Apparently, a bad case of the flu or COVID is the gift that keeps on giving. New research suggests severe respiratory infections could bump up your lung cancer risk years down the road. It seems major inflammation leaves a lasting scar your body remembers. Time to baby those lungs! 🫁

👇 Check it out:
https://www.sciencedaily.com/releases/2026/03/260313055130.htm

Amboss | One-Minute Telegram️

Mar 17, 2026, 01:00 PM

[poll]

Amboss | One-Minute Telegram️

Mar 16, 2026, 12:41 AM

It turns out your brain might just be having a massive low-battery moment. New research suggests depression could actually start with energy malfunctions in your cells, not just chemical imbalances. Think of it as a biological power outage rather than a simple mood swing. Basically, we might just need a jump-start! 🔋🧠

👇 Check it out:
https://www.sciencedaily.com/releases/2026/03/260312020107.htm

Amboss | One-Minute Telegram️

Mar 16, 2026, 12:41 AM

A mother brings her 10 month-old boy to the pediatrician for a check-up. His birth was without complications and his development to-date has been progressing normally. He currently crawls, pulls himself up to standing, says 'mama' and 'dada' nonspecifically, and responds when called by his name. However, his mother is concerned, as she has noted over the past several weeks that he has periods where he stops breathing when he gets frightened or upset. These episodes last for 20-30 seconds and are accompanied by his lips and face become bluish. His breathing has always resumed normally within 45 seconds after the start of the episode, and he acts normally afterwards. One instance resulted in the child passing out for a 5-10 seconds before a spontaneous recovery. Which of the following is the most appropriate management of this patient's condition?

Amboss | One-Minute Telegram️

Mar 16, 2026, 12:41 AM

[poll]

Amboss | One-Minute Telegram️

Mar 13, 2026, 09:32 AM

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